How aging and sleep health affect cognitive decline in cancer survivors
Official title: Patterns of biological, cognitive, and physical aging in cancer survivors and controls and the role of sleep health: Relevance for Alzheimer's Disease and Related Dementias
Funded at University of California Los Angeles · NIH-11056860 · Data updated 2026-11-12
This study is looking at how aging, memory changes, and sleep quality are connected in older women who have survived breast cancer, to help understand their risk of developing Alzheimer's and similar conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | June 15, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $782,758 |
| NIH project number | 5R01AG082348-03 |
| Project ID | NIH-11056860 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older women who have been diagnosed with breast cancer and are experiencing cognitive or sleep-related issues.
✕Less likely to help
Patients who are not breast cancer survivors or those without concerns related to cognitive decline or sleep health may not benefit from this research.
What this research studies
This research investigates the connections between biological aging, cognitive decline, and sleep health specifically in older women who are breast cancer survivors. By examining how these factors interact, the study aims to understand the potential risks for developing Alzheimer's disease and related dementias. The research employs a geroscience framework and includes both cancer survivors and control groups to provide a comprehensive view of these relationships over time. Participants will be monitored for changes in cognitive and physical health, as well as sleep patterns, to gather valuable data on these critical issues.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing cognitive decline and enhancing sleep health in cancer survivors, potentially reducing their risk of Alzheimer's disease.
How similar studies have gone: Previous research has shown promising results in understanding the links between aging, sleep, and cognitive decline, but this specific approach focusing on cancer survivors is relatively novel.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Carroll, Judith E — University of California Los Angeles
- Study coordinator: Carroll, Judith E
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.