How aging and environment shape our ability to navigate spaces

Influences of Environmental Geometry and Aging on Cognitive Mapping Mechanisms

NIH-funded research Georgia Institute of Technology · NIH-11086635

This study looks at how getting older and our surroundings affect how well we remember and navigate spaces, especially for older adults and those with Alzheimer’s, to help us understand more about memory changes as we age.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGeorgia Institute of Technology NIH-funded
Lab location1 site (Atlanta, United States)
Project IDNIH-11086635 on NIH RePORTER

What this research studies

This research investigates how the brain's entorhinal cortex, which helps us form and remember cognitive maps, is influenced by aging and environmental factors. Using advanced virtual navigation and fMRI techniques, the study aims to uncover how changes in our surroundings affect our spatial memory and navigation abilities, particularly in older adults and those with Alzheimer’s-related dementia. By understanding these mechanisms, the research seeks to clarify the relationship between cognitive decline and environmental geometry.

Who could benefit from this research

Good fit: Ideal candidates for this research include older adults and individuals diagnosed with Alzheimer’s-related dementia or those at risk due to genetic factors.

Not a fit: Patients who are not experiencing cognitive decline or do not have any age-related cognitive impairments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for enhancing navigation skills and cognitive function in aging populations and individuals with Alzheimer’s-related dementia.

How similar studies have performed: Previous research has shown promising results in understanding cognitive mapping and navigation in relation to aging and dementia, suggesting that this approach could yield valuable insights.

Where this research is happening

Atlanta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions age associated diseaseage associated disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.