How aging affects the immune system's response to lung cancer
Genetic analysis of aging on immune responses to lung cancer
This study is looking at how getting older affects the immune system's response to lung cancer, with the hope of finding better treatments for older adults battling this disease.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11074422 on NIH RePORTER |
What this research studies
This research investigates how aging influences the immune system's ability to respond to lung cancer. By using advanced techniques like genetically engineered mouse models and CRISPR technology, the researchers aim to analyze the genetic factors that affect immune responses in older individuals. The study will focus on understanding how these immune responses change with age and how they impact tumor growth and initiation. Patients may benefit from insights that could lead to improved cancer treatments tailored for older adults.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults who are at risk for or have been diagnosed with lung cancer.
Not a fit: Patients who are younger and do not have lung cancer may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective cancer treatments specifically designed for older patients.
How similar studies have performed: Other research has shown promising results in understanding the immune system's role in cancer, but this specific approach using advanced genetic techniques is relatively novel.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Winslow, Monte Meier — Stanford University
- Study coordinator: Winslow, Monte Meier
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.