How aging affects inflammation and heart disease
Inflammation-resolution impairments in aging and atherosclerosis
This study is looking at how getting older affects inflammation in the body and how that might lead to heart problems, especially in older adults, with the hope of finding new ways to help treat heart disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albany Medical College NIH-funded |
| Lab location | 1 site (Albany, United States) |
| Project ID | NIH-11083016 on NIH RePORTER |
What this research studies
This research investigates how aging influences inflammation and its role in heart disease, specifically atherosclerosis. It focuses on understanding the mechanisms that lead to persistent inflammation in older adults and how this impacts cardiovascular health. The study aims to explore the balance between harmful inflammatory substances and those that promote healing, with the goal of developing new treatments for heart disease in the context of aging. By studying aged mice, researchers will identify potential therapeutic strategies to improve inflammation resolution.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults who are at risk for or have been diagnosed with atherosclerotic cardiovascular disease.
Not a fit: Patients who are younger and do not have any cardiovascular disease or inflammation-related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve heart health and reduce inflammation in older patients.
How similar studies have performed: Other research has shown promising results in understanding inflammation and aging, suggesting that this approach could yield valuable insights.
Where this research is happening
Albany, United States
- Albany Medical College — Albany, United States (Active)
Researchers
- Principal investigator: Fredman, Gabrielle — Albany Medical College
- Study coordinator: Fredman, Gabrielle
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.