How aging affects inflammation and fat metabolism
Inflammation, Lipid Metabolism and Senescence
This study looks at how getting older affects our immune and fat cells, especially how they work together and how this might lead to health issues, with the goal of finding ways to help older adults stay healthier.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10848465 on NIH RePORTER |
What this research studies
This research investigates the relationship between aging, inflammation, and lipid metabolism, particularly focusing on how immune cells and fat cells interact as we age. It explores the role of lipids in influencing B-cell behavior and how these changes can lead to increased oxidative stress and cellular aging in adipose tissue. By understanding these mechanisms, the research aims to uncover potential therapeutic targets that could improve metabolic health in older adults.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing metabolic issues related to aging, such as obesity or insulin resistance.
Not a fit: Patients who are younger and do not have metabolic disorders related to aging may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing age-related metabolic disorders and improving overall health in older adults.
How similar studies have performed: Previous research has shown promising results in understanding the role of inflammation and lipid metabolism in aging, suggesting that this approach could yield valuable insights.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Camell, Christina — University of Minnesota
- Study coordinator: Camell, Christina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.