How aging affects fat tissue and insulin resistance
Inflammation and insulin resistance in aging
['FUNDING_R01'] · BAYLOR COLLEGE OF MEDICINE · NIH-10994142
This study is looking at how getting older affects fat in our bodies and how that might lead to problems with insulin, especially by checking out the role of immune cells in fat tissue, to help us understand why older folks might gain more weight and have metabolic issues.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BAYLOR COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10994142 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between aging, inflammation in fat tissue, and insulin resistance. It focuses on how the body's fat cells change with age, particularly looking at the role of different types of immune cells in fat tissue. By studying these changes, the research aims to understand why older individuals may experience increased fat accumulation and metabolic issues. The approach includes examining the behavior of specific immune cells and their impact on fat metabolism in aging.
Who could benefit from this research
Good fit: Ideal candidates for this research are middle-aged individuals experiencing weight gain or metabolic issues related to aging.
Not a fit: Patients who are not middle-aged or do not have issues related to obesity or insulin resistance may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating obesity and insulin resistance in older adults.
How similar studies have performed: Previous research has shown promising results in understanding the role of immune cells in fat metabolism, suggesting that this approach may yield valuable insights.
Where this research is happening
HOUSTON, UNITED STATES
- BAYLOR COLLEGE OF MEDICINE — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WU, HUAIZHU — BAYLOR COLLEGE OF MEDICINE
- Study coordinator: WU, HUAIZHU
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.