How aging affects emotion regulation in mood disorders

Brain-based Mechanisms of Emotion Regulation in Aging and Mood Disorders

['FUNDING_R01'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-10974481

This study is looking at how getting older affects the way people with mood disorders, like bipolar disorder and depression, manage their emotions, and it hopes to find ways to improve emotional health for older adults.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorBRIGHAM AND WOMEN'S HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10974481 on ClinicalTrials.gov

What this research studies

This research investigates how aging influences the ability to regulate emotions in individuals with mood disorders like bipolar disorder and major depressive disorder. It aims to understand the brain mechanisms involved in emotion regulation and how these mechanisms may differ between older adults with mood disorders and healthy individuals. By enrolling a diverse group of participants aged 41-80, the study will assess various factors such as cognitive control and emotional biases to identify age-related changes in emotion regulation. The findings could help tailor interventions for better emotional health in older adults.

Who could benefit from this research

Good fit: Ideal candidates for this research include adults aged 41-80 with stable mood disorders like bipolar disorder or major depressive disorder.

Not a fit: Patients outside the age range of 41-80 or those without mood disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for managing mood disorders in older adults, enhancing their emotional well-being.

How similar studies have performed: Previous research has shown promising results in understanding emotion regulation across different age groups, suggesting that this approach could yield valuable insights.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Affective Disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.