How aging affects cognitive control in older adults and those with mild cognitive impairment

Aging hippocampus and cognitive control in health and MCI

NIH-funded research College at Oswego · NIH-11089345

This study is looking at how getting older affects our ability to think and make decisions, especially for older adults with mild cognitive impairment, by exploring how a part of the brain called the hippocampus helps with these skills.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCollege at Oswego NIH-funded
Lab location1 site (Oswego, United States)
Project IDNIH-11089345 on NIH RePORTER

What this research studies

This research investigates the impact of aging on cognitive control, which is essential for daily activities in older adults. It focuses on understanding how the hippocampus, a brain region involved in memory and contextual processing, contributes to cognitive control deficits, particularly in individuals with mild cognitive impairment (MCI). By employing innovative behavioral tasks, the study aims to differentiate between proactive and reactive cognitive processes and their relationship with age-related changes. Participants will engage in tasks designed to assess their cognitive control abilities and the underlying neural mechanisms involved.

Who could benefit from this research

Good fit: Ideal candidates for this research include older adults and individuals diagnosed with mild cognitive impairment.

Not a fit: Patients who are younger and do not have cognitive impairments may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for enhancing cognitive function in older adults and those with mild cognitive impairment.

How similar studies have performed: Previous research has shown promising results in understanding cognitive control in aging, but this study aims to explore novel aspects of the relationship between hippocampal function and cognitive processes.

Where this research is happening

Oswego, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions age associated diseaseage associated disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.