How aging affects cognitive control in older adults and those with mild cognitive impairment
Official title: Aging hippocampus and cognitive control in health and MCI
Funded at College at Oswego · NIH-11089345 · Data updated 2026-11-12
This study is looking at how getting older affects our ability to think and make decisions, especially for older adults with mild cognitive impairment, by exploring how a part of the brain called the hippocampus helps with these skills.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | College at Oswego NIH-funded |
| Lab location | 1 site (Oswego, United States) |
| Project start | September 1, 2022 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $411,032 |
| NIH project number | 5R01AG078266-04 |
| Project ID | NIH-11089345 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include older adults and individuals diagnosed with mild cognitive impairment.
✕Less likely to help
Patients who are younger and do not have cognitive impairments may not receive any benefit from this research.
What this research studies
This research investigates the impact of aging on cognitive control, which is essential for daily activities in older adults. It focuses on understanding how the hippocampus, a brain region involved in memory and contextual processing, contributes to cognitive control deficits, particularly in individuals with mild cognitive impairment (MCI). By employing innovative behavioral tasks, the study aims to differentiate between proactive and reactive cognitive processes and their relationship with age-related changes. Participants will engage in tasks designed to assess their cognitive control abilities and the underlying neural mechanisms involved.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for enhancing cognitive function in older adults and those with mild cognitive impairment.
How similar studies have gone: Previous research has shown promising results in understanding cognitive control in aging, but this study aims to explore novel aspects of the relationship between hippocampal function and cognitive processes.
Where this research is happening
-
College at Oswego
Oswego, United States Active
Researchers
- Principal investigator: Hu, Sien — College at Oswego
- Study coordinator: Hu, Sien
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.