How aging affects cervical cancer outcomes in women with HIV in Zambia

The Impact of Biologic Aging on Immunity-Related Cervical Cancer Outcome Disparities Among Women Living with HIV in Zambia

NIH-funded research University of Tx Md Anderson Can Ctr · NIH-10931755

This study is looking at how aging affects cervical cancer treatment in women with HIV in Zambia, aiming to find ways to improve care and support for those who may not have easy access to screening and treatment.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Tx Md Anderson Can Ctr NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-10931755 on NIH RePORTER

What this research studies

This research investigates the relationship between biological aging and cervical cancer outcomes among women living with HIV in Zambia. It focuses on how premature aging, often seen in individuals with HIV, may influence the effectiveness of standard treatments like chemoradiation therapy. By examining the epigenetic changes associated with aging, the study aims to understand disparities in cancer progression and treatment responses in this vulnerable population. The research seeks to improve access to cervical cancer screening and treatment for women in underserved communities.

Who could benefit from this research

Good fit: Ideal candidates for this research are women living with HIV in Zambia, particularly those who are at risk for cervical cancer.

Not a fit: Patients who do not live in Zambia or who do not have HIV may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies and outcomes for women living with HIV who are at risk for cervical cancer.

How similar studies have performed: Previous research has shown that understanding biological aging can impact treatment outcomes in cancer, suggesting this approach may yield valuable insights.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.