How aging affects brain networks in Alzheimer's disease
Interactive Effects of Aging and AD on Brain Networks
This study is looking at how getting older affects the brain and its connection to Alzheimer's disease, using special brain scans to find out which areas might be more at risk, so we can better diagnose and treat the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11076351 on NIH RePORTER |
What this research studies
This research investigates the interplay between aging and Alzheimer's disease (AD) by examining how age-related changes in the brain influence the development and progression of AD. It utilizes advanced MRI techniques to analyze microstructural properties of the brain, focusing on aspects like neurite morphology and network-level organization. By understanding these interactions, the study aims to identify brain regions that are particularly vulnerable to AD pathology, which could lead to improved diagnostic and therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older, particularly those at risk for or diagnosed with Alzheimer's disease.
Not a fit: Patients younger than 65 or those without any risk factors for Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of Alzheimer's disease and lead to better prevention and treatment strategies for older adults.
How similar studies have performed: Previous research has shown promising results in understanding the effects of aging on brain health, but this specific approach focusing on microstructural changes in the context of Alzheimer's disease is relatively novel.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Hosseini, Hadi — Stanford University
- Study coordinator: Hosseini, Hadi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.