How age and sex affect blood flow response to spinal cord injury
Official title: Differential microvascular response to trauma in the spinal cord with sex and age
Funded at University of Washington · NIH-11022785 · Data updated 2026-11-12
This study is looking at how age and sex affect blood flow changes after a spinal cord injury, especially in older adults, to find better ways to help people recover and protect their spinal cords from further damage.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | January 15, 2025 |
| Project end | December 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $506,696 |
| NIH project number | 1R01NS140285-01 |
| Project ID | NIH-11022785 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults aged 65 and above who have experienced a spinal cord injury.
✕Less likely to help
Patients under the age of 65 or those without spinal cord injuries may not benefit from this research.
What this research studies
This research investigates how the microvascular response to spinal cord injury (SCI) differs based on age and sex, particularly focusing on older adults. It aims to understand the changes in blood flow that occur after trauma to the cervical spine, which is crucial for preventing further damage and improving recovery. Using a rodent model, the study will evaluate blood flow parameters to identify potential interventions that could enhance recovery outcomes for patients with SCI. The findings could lead to new strategies for protecting the spinal cord from secondary damage following injury.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments that enhance recovery and quality of life for patients with spinal cord injuries, particularly in older adults.
How similar studies have gone: Previous research has shown promising results in understanding microvascular responses in other contexts, but this specific approach focusing on age and sex in spinal cord injuries is relatively novel.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Khaing, Zin Z — University of Washington
- Study coordinator: Khaing, Zin Z
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.