How age and race affect immunosuppression after kidney transplants
Age and Race Influences on Immunosuppression after Renal Transplant
['FUNDING_R01'] · STATE UNIVERSITY OF NEW YORK AT BUFFALO · NIH-10441282
This study is looking at how age and race affect how well certain medications work for people who have had a kidney transplant, especially focusing on older adults and African Americans, to help create better, personalized treatment plans for everyone.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STATE UNIVERSITY OF NEW YORK AT BUFFALO (nih funded) |
| Locations | 1 site (AMHERST, UNITED STATES) |
| Trial ID | NIH-10441282 on ClinicalTrials.gov |
What this research studies
This research investigates how factors like age and race influence the effectiveness of immunosuppressive medications used after kidney transplants. It focuses on understanding the differences in how older adults and African Americans respond to common drugs like tacrolimus and mycophenolic acid, which are crucial for preventing organ rejection. By studying these variations, the research aims to develop more personalized treatment plans that consider individual patient characteristics. This could lead to improved outcomes for kidney transplant recipients.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults and African American individuals who are undergoing or have undergone kidney transplantation.
Not a fit: Patients who are not undergoing kidney transplantation or those who do not belong to the age or racial groups being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized immunosuppressive therapies for kidney transplant patients, improving their chances of long-term organ survival.
How similar studies have performed: Previous research has shown that understanding pharmacokinetics and pharmacodynamics can lead to better individualized treatment strategies, suggesting potential success for this approach.
Where this research is happening
AMHERST, UNITED STATES
- STATE UNIVERSITY OF NEW YORK AT BUFFALO — AMHERST, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TORNATORE, KATHLEEN M — STATE UNIVERSITY OF NEW YORK AT BUFFALO
- Study coordinator: TORNATORE, KATHLEEN M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.