How age and depression affect memory in diverse adults
Official title: Executive contributions to the “double jeopardy” of depressive symptoms and age on episodic memory in racially diverse adults
Funded at University of Texas at Austin · NIH-11098712 · Data updated 2026-11-12
This study is looking at how age and depression affect memory problems in adults from different racial backgrounds, aiming to help us understand how these issues might lead to cognitive decline and Alzheimer's disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas at Austin NIH-funded |
| Lab location | 1 site (Austin, United States) |
| Project start | June 1, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $755,597 |
| NIH project number | 5R01AG084235-02 |
| Project ID | NIH-11098712 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults aged 21 and older from Black, Mexican, and non-Hispanic White backgrounds who experience depressive symptoms.
✕Less likely to help
Patients who are younger than 21 or do not experience depressive symptoms may not benefit from this research.
What this research studies
This research investigates the interaction between age and depressive symptoms and how they contribute to memory impairment, particularly in racially diverse adults. The study aims to understand the 'double jeopardy' effect of these factors on episodic memory and the risk of cognitive decline and Alzheimer's disease. By enrolling 330 participants from Black, Mexican, and non-Hispanic White backgrounds, the research will assess various dimensions of depression and their relationship with memory and executive functioning. The goal is to uncover the underlying causes of these impairments and explore how race-related factors may influence them.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and interventions for memory impairments associated with aging and depression in diverse populations.
How similar studies have gone: While there is emerging evidence on the effects of age and depression on memory, this specific approach focusing on ethnoracial disparities is relatively novel and has not been extensively tested.
Where this research is happening
-
University of Texas at Austin
Austin, United States Active
Researchers
- Principal investigator: Duarte, Audrey — University of Texas at Austin
- Study coordinator: Duarte, Audrey
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.