How age and depression affect memory in diverse adults

Executive contributions to the “double jeopardy” of depressive symptoms and age on episodic memory in racially diverse adults

NIH-funded research University of Texas at Austin · NIH-11098712

This study is looking at how age and depression affect memory problems in adults from different racial backgrounds, aiming to help us understand how these issues might lead to cognitive decline and Alzheimer's disease.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas at Austin NIH-funded
Lab location1 site (Austin, United States)
Project IDNIH-11098712 on NIH RePORTER

What this research studies

This research investigates the interaction between age and depressive symptoms and how they contribute to memory impairment, particularly in racially diverse adults. The study aims to understand the 'double jeopardy' effect of these factors on episodic memory and the risk of cognitive decline and Alzheimer's disease. By enrolling 330 participants from Black, Mexican, and non-Hispanic White backgrounds, the research will assess various dimensions of depression and their relationship with memory and executive functioning. The goal is to uncover the underlying causes of these impairments and explore how race-related factors may influence them.

Who could benefit from this research

Good fit: Ideal candidates for this research include adults aged 21 and older from Black, Mexican, and non-Hispanic White backgrounds who experience depressive symptoms.

Not a fit: Patients who are younger than 21 or do not experience depressive symptoms may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for memory impairments associated with aging and depression in diverse populations.

How similar studies have performed: While there is emerging evidence on the effects of age and depression on memory, this specific approach focusing on ethnoracial disparities is relatively novel and has not been extensively tested.

Where this research is happening

Austin, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.