How adolescent racism and discrimination affect later substance use and mental health

Measuring the impact of structural racism and discrimination during adolescence on substance use, psychological distress

NIH-funded research Research Triangle Institute · NIH-11035106

This project looks at whether experiences of racism and discrimination during youth are linked to later substance use, psychological distress, criminal-legal involvement, and treatment-seeking for people who grew up in racially diverse rural communities.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionResearch Triangle Institute NIH-funded
Lab location1 site (Research Triangle Park, United States)
Project IDNIH-11035106 on NIH RePORTER

What this research studies

You would be joining a long-term group of people who were in 6th–8th grade in three North Carolina counties in 2002 and have been followed into adulthood. Researchers will collect one more survey and link your responses to school, peer network, neighborhood, and administrative records to capture experiences of structural racism and discrimination during adolescence. They will examine how those adolescent experiences relate to adult substance use, mental health distress, interactions with the criminal legal system, and whether people sought treatment. The team will also look for community resilience factors that might protect people and suggest possible places to intervene.

Who could benefit from this research

Good fit: Ideal candidates are adults who were in 6th–8th grade in the three participating North Carolina public-school counties in 2002 and who are willing to complete a survey and allow linkage to records.

Not a fit: People who were not part of the original cohort or who cannot provide linkable records are unlikely to be eligible or to directly benefit from participating.

Why it matters

Potential benefit: If successful, this work could point to community- and school-level actions that reduce long-term harms from adolescent racism and improve prevention and treatment connections.

How similar studies have performed: Longitudinal studies have linked childhood adversity to adult substance use and mental health, but combining detailed peer, school, and neighborhood measures to capture structural racism across adolescence is a newer approach.

Where this research is happening

Research Triangle Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.