How adolescent alcohol use affects immune response to infections
Official title: CNS-mediated fever after Adolescent Intermittent Ethanol
Funded at State University of Ny,binghamton · NIH-11063159 · Data updated 2026-11-12
This study looks at how binge drinking during the teenage years might affect the immune system's ability to fight off infections, like COVID-19, to help us understand why some young people may get sicker than others.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of Ny,binghamton NIH-funded |
| Lab location | 1 site (Binghamton, United States) |
| Project start | April 1, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $426,682 |
| NIH project number | 5R01AA030469-03 |
| Project ID | NIH-11063159 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 12 to 20 who have a history of alcohol use or exposure.
✕Less likely to help
Patients who have never consumed alcohol or are outside the adolescent age range may not benefit from this research.
What this research studies
This research investigates the impact of intermittent alcohol exposure during adolescence on the immune system's response to infections, particularly viral infections like COVID-19. It aims to understand how binge drinking in young individuals may alter their immune function and increase vulnerability to severe disease outcomes. By studying both human and animal models, the research seeks to uncover the mechanisms behind these changes and their implications for health. The findings could help identify at-risk adolescents and inform preventive strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of health risks associated with adolescent alcohol use, particularly in relation to viral infections.
How similar studies have gone: Previous research has indicated that alcohol exposure can negatively impact immune function, suggesting that this study builds on established findings rather than exploring a completely novel area.
Where this research is happening
-
State University of Ny,binghamton
Binghamton, United States Active
Researchers
- Principal investigator: Deak, Terrence — State University of Ny,binghamton
- Study coordinator: Deak, Terrence
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.