How adolescent alcohol abuse affects stress and PTSD risk in adults
Official title: Adolescent Alcohol Abuse, Traumatic Stress, and Vulnerability to Development of PTSD
Funded at Medical University of South Carolina · NIH-10758204 · Data updated 2026-11-12
This study is looking at how drinking alcohol as a teenager might affect your ability to handle stress and develop PTSD later in life, and it's for anyone interested in understanding the long-term effects of early alcohol use on mental health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical University of South Carolina NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project start | January 1, 2020 |
| Project end | December 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $450,355 |
| NIH project number | 5R01AA027706-05 |
| Project ID | NIH-10758204 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 12-20 who have a history of alcohol use and may be at risk for developing PTSD.
✕Less likely to help
Patients who have not engaged in alcohol use during adolescence or who do not have a history of trauma may not benefit from this research.
What this research studies
This research investigates the relationship between adolescent alcohol abuse and the development of Post-Traumatic Stress Disorder (PTSD) in adulthood. It aims to understand how early alcohol use impacts brain function and behavior, particularly in response to traumatic stress events. By examining the neurocircuitry involved, the study seeks to identify why individuals with a history of alcohol abuse during adolescence may struggle with stress resilience later in life. The research employs a combination of behavioral assessments and neuroimaging techniques to explore these connections.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for PTSD and alcohol use disorder in adolescents and adults.
How similar studies have gone: Previous research has indicated a strong link between adolescent alcohol use and later mental health issues, suggesting that this study's approach is grounded in established findings.
Where this research is happening
-
Medical University of South Carolina
Charleston, United States Active
Researchers
- Principal investigator: Chandler, L Judson — Medical University of South Carolina
- Study coordinator: Chandler, L Judson
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.