How adiponectin affects blood vessel health as we age
Official title: Role of Adiponectin in Reversal of Age-related Vascular Dysfunction
Funded at Kansas State University · NIH-10988256 · Data updated 2026-11-12
This study is looking at how a protein called adiponectin, which is related to fat, can help improve blood vessel health as we get older, and it will explore whether doing aerobic exercise can boost this protein and keep our blood vessels healthy in older adults.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kansas State University NIH-funded |
| Lab location | 1 site (Manhattan, United States) |
| Project start | February 15, 2023 |
| Project end | November 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $358,937 |
| NIH project number | 5R01HL166591-04 |
| Project ID | NIH-10988256 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults experiencing age-related vascular dysfunction or those interested in improving their cardiovascular health through exercise.
✕Less likely to help
Patients who are younger and do not have any cardiovascular issues may not benefit from this research.
What this research studies
This research investigates the role of adiponectin, a protein linked to fat tissue, in reversing the negative effects of aging on blood vessels. The study will explore how aerobic exercise training can increase adiponectin levels and improve vascular health in older adults. By understanding the cellular signals involved, the research aims to identify how exercise can help maintain healthy blood vessels as we age. Participants may engage in aerobic activities while researchers monitor changes in their vascular function and adiponectin levels.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving cardiovascular health in older adults through exercise and adiponectin modulation.
How similar studies have gone: Previous research has shown that exercise can improve vascular health in older adults, but the specific role of adiponectin in this process is still being explored.
Where this research is happening
-
Kansas State University
Manhattan, United States Active
Researchers
- Principal investigator: Delp, Judy M — Kansas State University
- Study coordinator: Delp, Judy M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.