NIH-funded research R01 grant

How ADHD and thinking skills affect reading in children with dyslexia

Official title: Influence of ADHD and Executive Functions on Developmental Dyslexia

Funded at Mgh Institute of Health Professions · NIH-11325068 · Data updated 2026-11-12

The team will follow 8–10 year-old children with dyslexia (with and without ADHD) and typical readers over three years to link thinking skills, brain measures, and reading progress.

More ADHD research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMgh Institute of Health Professions
NIH-funded
Lab location1 site (Charlestown, UNITED STATES)
Project startJuly 1, 2022
Project endMarch 31, 2027
Funding year2026
Award (this year)$664,630
NIH project number5R01HD106122-05
Project IDNIH-11325068 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are children aged roughly 8–10 in grades three or four who have been diagnosed with dyslexia or dyslexia plus ADHD, or who are typical readers for comparison.

Less likely to help

Children outside the 8–10 age range or without reading concerns would not match this study and likely would not benefit directly.

What this research studies

If your child is in third or fourth grade, researchers will invite them to join one of three groups: typical readers, children with dyslexia, or children with both dyslexia and ADHD. Each child will come for three yearly visits with tests of reading, attention, and executive functions plus brain scans to track changes over time. The study plans about 80 children per group and will use behavioral tests and neuroimaging to separate the effects of ADHD symptoms from underlying thinking-skill weaknesses. Results aim to clarify why some children struggle with reading and guide better assessment and targeted help in school.

Why it matters

Potential benefit: If successful, the findings could help clinicians and schools tailor assessments and interventions to a child's specific ADHD symptoms or thinking-skill needs.

How similar studies have gone: Previous research has linked executive function and ADHD to reading problems, but few long-term brain imaging studies have followed children across multiple years, so this approach adds important new longitudinal data.

Where this research is happening

  • Mgh Institute of Health Professions
    Charlestown, United States
    Active

Researchers

  • Principal investigator: Christodoulou, Joanna — Mgh Institute of Health Professions
  • Study coordinator: Christodoulou, Joanna

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.