How Acinetobacter baumannii manages zinc levels for survival
Strategies for Acinetobacter baumannii to Maintain Zinc Homeostasis
This study is looking at how a germ called Acinetobacter baumannii manages its zinc levels to survive, especially when there's not enough zinc around, and it hopes to find new ways to treat infections caused by this germ that could help patients.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project ID | NIH-10874589 on NIH RePORTER |
What this research studies
This research investigates how the bacterium Acinetobacter baumannii maintains zinc homeostasis, which is crucial for its survival and growth. The study focuses on understanding the mechanisms that this pathogen uses to control zinc levels, especially under conditions of zinc limitation. By identifying key proteins involved in this process, the research aims to develop new metal-based therapies that could target these mechanisms. Patients may benefit from this work as it could lead to novel treatments for infections caused by this opportunistic pathogen.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with infections caused by Acinetobacter baumannii.
Not a fit: Patients with infections caused by other types of bacteria may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for treating infections caused by Acinetobacter baumannii.
How similar studies have performed: Other research has shown promise in targeting metal homeostasis in bacteria, suggesting that this approach could be effective.
Where this research is happening
Nashville, UNITED STATES
- Vanderbilt University — Nashville, United States (Active)
Researchers
- Principal investigator: Miller, Jeanette Marie — Vanderbilt University
- Study coordinator: Miller, Jeanette Marie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.