How a specific immune response affects recovery in older women after a stroke
Contribution of IL6 trans signaling in older females after ischemic stroke
['FUNDING_R01'] · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · NIH-11061872
This study is looking at how a specific immune response affects recovery after a stroke in older women, with the goal of finding ways to help them heal better and improve their movement and thinking skills.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-11061872 on ClinicalTrials.gov |
What this research studies
This research investigates the role of IL6 trans signaling in older females who have experienced an ischemic stroke. It aims to understand how this immune response differs between sexes and how it impacts recovery outcomes. By focusing on the molecular mechanisms involved, particularly the role of microglia and inflammatory responses, the study seeks to identify potential therapeutic targets that could improve recovery for elderly women after a stroke. The research will involve analyzing the effects of IL6 signaling on both motor function and cognitive impairment following stroke.
Who could benefit from this research
Good fit: Ideal candidates for this research are older females aged 65 and above who have suffered an ischemic stroke.
Not a fit: Patients who are younger than 65 or who have not experienced an ischemic stroke may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for older women recovering from strokes, enhancing their long-term functional outcomes.
How similar studies have performed: Previous research has shown that targeting inflammatory pathways can improve recovery outcomes in stroke patients, suggesting that this approach may also be effective in older females.
Where this research is happening
HOUSTON, UNITED STATES
- UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHAUHAN, ANJALI — UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
- Study coordinator: CHAUHAN, ANJALI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.