How a specific brain area influences vision and movement

The Influence of the Pretectum on the Visual Thalamus

['FUNDING_R01'] · UNIVERSITY OF LOUISVILLE · NIH-10915626

This study is looking at a small part of the brain called the pretectum to see how it helps process what we see and control our movements, which could help us understand more about how our vision works and how it affects our actions.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF LOUISVILLE (nih funded)
Locations1 site (LOUISVILLE, UNITED STATES)
Trial IDNIH-10915626 on ClinicalTrials.gov

What this research studies

This research investigates the role of the pretectum, a lesser-known area of the brain, in shaping how thalamic neurons process visual information and coordinate movement. By employing advanced techniques such as 2-photon imaging and rabies tracing, the researchers aim to understand the connections and functions of pretectal circuits. The study will explore how these circuits affect visual behavior and the response properties of neurons involved in vision. This multifaceted approach seeks to bridge the gap between cellular mechanisms and behavioral outcomes.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would include individuals with visual processing disorders or conditions like amblyopia.

Not a fit: Patients with purely structural eye issues unrelated to neural processing may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment of visual disorders, potentially enhancing vision and movement coordination in affected patients.

How similar studies have performed: While the specific focus on the pretectum is relatively novel, similar approaches in studying brain circuits have shown promise in understanding visual processing in other contexts.

Where this research is happening

LOUISVILLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.