How a specific bacterium affects fat and metabolism
Regulation of metabolic diseases by Clostridium immunis
['FUNDING_OTHER'] · DUKE UNIVERSITY · NIH-11091384
This study is looking at a new type of bacteria called Clostridium immunis to see how it might help manage body fat and improve conditions like type 2 diabetes, which could lead to new treatment options for people dealing with these metabolic issues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DUKE UNIVERSITY (nih funded) |
| Locations | 1 site (DURHAM, UNITED STATES) |
| Trial ID | NIH-11091384 on ClinicalTrials.gov |
What this research studies
This research investigates the role of Clostridium immunis, a newly identified bacterium, in regulating visceral adipose tissue (VAT) and its impact on metabolic diseases like type 2 diabetes. The study aims to understand the mechanisms by which this bacterium and its secreted substances can reduce body weight and triglycerides. By examining immune responses and energy expenditure, the research seeks to uncover how this bacterium can potentially alter fat accumulation in the body. Patients may benefit from insights into new treatments targeting metabolic disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults experiencing abdominal obesity or metabolic syndrome.
Not a fit: Patients with metabolic disorders unrelated to visceral fat accumulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to novel therapeutic strategies for managing obesity and type 2 diabetes.
How similar studies have performed: Previous research has shown promise in using gut microbiota to influence metabolic health, suggesting potential for success in this novel approach.
Where this research is happening
DURHAM, UNITED STATES
- DUKE UNIVERSITY — DURHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SURANA, NEERAJ K — DUKE UNIVERSITY
- Study coordinator: SURANA, NEERAJ K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus