How a protein affects immune cells involved in allergies and infections
Official title: Regulation of tissue-resident helper type 2 T cells by fatty acid transport protein 4 (FATP4)
Funded at Johns Hopkins University · NIH-11055383 · Data updated 2026-11-12
This study is looking at how a protein called FATP4 affects certain immune cells that help our body respond to allergies and infections, with the goal of finding new ways to improve immune responses or reduce allergic reactions, especially for people with asthma.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | April 1, 2023 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $76,756 |
| NIH project number | 5F32AI176630-03 |
| Project ID | NIH-11055383 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals suffering from allergic conditions such as asthma or food allergies.
✕Less likely to help
Patients with non-allergic conditions or those not affected by immune response disorders may not benefit from this research.
What this research studies
This research investigates the role of fatty acid transport protein 4 (FATP4) in regulating a specific type of immune cells known as helper type 2 T cells, which are important in responding to allergens and infections. The study aims to understand how FATP4 influences the metabolism and function of these cells, particularly in the context of allergic responses and conditions like asthma. By examining the mechanisms behind FATP4's action, the research hopes to identify new therapeutic strategies to enhance protective immune responses or mitigate harmful allergic reactions.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for allergic disorders and asthma by targeting the metabolic pathways of immune cells.
How similar studies have gone: Other research has shown promising results in understanding immune cell metabolism, suggesting that this approach could yield significant insights.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Kania, Anna K. — Johns Hopkins University
- Study coordinator: Kania, Anna K.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.