How a new wound dressing helps heal difficult ulcers
Official title: Effects of Wound Dressing's Vapor and Gas Permeability on Ischemic Ulcer Healing
Funded at University of Nebraska Omaha · NIH-11035253 · Data updated 2026-11-12
This study is testing a new type of wound dressing that helps heal painful ulcers on the legs caused by poor blood flow, specifically for people with peripheral artery disease, by keeping the wound moist and protected from infection.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Omaha NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project start | February 15, 2024 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $248,173 |
| NIH project number | 5P20GM152301-02 |
| Project ID | NIH-11035253 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients suffering from ischemic ulcers due to peripheral artery disease who have not responded well to standard treatments.
✕Less likely to help
Patients with ulcers not related to ischemic conditions or those who have already undergone amputation may not benefit from this research.
What this research studies
This research investigates a novel wound dressing designed to improve the healing of ischemic ulcers caused by poor blood flow in the lower extremities. The study focuses on the dressing's ability to maintain an optimal environment for healing while preventing infection, which is crucial for patients with peripheral artery disease (PAD). By using biopolymer nanofibers, the dressing aims to balance moisture levels and promote tissue regeneration, addressing the challenges faced by traditional wound care methods. Patients with severe ulcers will be monitored to assess the effectiveness of this innovative approach.
Why it matters
Potential benefit: If successful, this research could lead to improved healing outcomes for patients with hard-to-treat ischemic ulcers, potentially reducing the need for amputations.
How similar studies have gone: Previous research has shown success with similar biopolymer dressings in treating thermal burns, indicating potential for effectiveness in ulcer healing.
Where this research is happening
-
University of Nebraska Omaha
Omaha, United States Active
Researchers
- Principal investigator: Salkovskiy, Yury — University of Nebraska Omaha
- Study coordinator: Salkovskiy, Yury
Related research
Other NIH-funded projects on the same topics.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.