How a high fat diet affects body clocks and energy use
Official title: Effect of high fat diet on the circadian system and on circadian rhythms in energy intake and expenditure
Funded at Brigham and Women's Hospital · NIH-10896927 · Data updated 2026-11-12
This study looks at how eating a lot of fatty foods affects our body's natural clock that helps manage energy use, with the goal of finding ways to improve diet and help with weight management and related health issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $789,491 |
| NIH project number | 5R01HL167746-02 |
| Project ID | NIH-10896927 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals struggling with obesity or metabolic disorders who are interested in understanding how diet affects their health.
✕Less likely to help
Patients who are not affected by obesity or metabolic disorders may not receive direct benefits from this research.
What this research studies
This research investigates the impact of high fat diets on the body's circadian system, which regulates energy intake and expenditure. By examining how dietary fat influences circadian rhythms, the study aims to uncover mechanisms that may contribute to obesity and metabolic disorders. The research utilizes animal models to explore the relationship between diet, circadian disruption, and energy balance, providing insights that could lead to better dietary recommendations for weight management.
Why it matters
Potential benefit: If successful, this research could lead to improved dietary guidelines that help manage obesity and related metabolic disorders.
How similar studies have gone: Previous research has shown that dietary composition can significantly affect circadian rhythms and metabolic health, indicating a promising area of study.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Scheer, Frank a — Brigham and Women's Hospital
- Study coordinator: Scheer, Frank a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.