NIH-funded research R01 grant

HOPE for Older Adults with HIV: a health promotion program for better heart and mental health

Official title: Strengthening Hearts and Minds: A Health Promotion Strategy for Older Adults with HIV

Funded at University of Miami School of Medicine · NIH-11468612 · Data updated 2026-11-12

A program called HOPE helps adults aged 50 and up living with HIV improve heart health and mental well-being through structured activities and education.

More Health Promotion research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Miami School of Medicine
NIH-funded
Lab location1 site (Coral Gables, United States)
Project startAugust 15, 2026
Project endJuly 31, 2031
Funding year2026
Award (this year)$783,407
NIH project number1R01AG099754-01A1
Project IDNIH-11468612 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults aged 50 or older living with HIV who have documented cardiovascular risk and are willing to participate in a structured health-promotion program.

Less likely to help

Patients without cardiovascular risk or those unable to participate in a behavioral program may see limited or no benefit.

What this research studies

This NIH grant funds a trial enrolling 180 adults aged 50+ with HIV who have cardiovascular risk. Participants are randomized to the HOPE health promotion program or a psychoeducation control, with assessments at baseline, after the intervention, and at 6 and 12 months to track cardiovascular risk, mental health, and HIV-related outcomes. The study aims to see if HOPE can more effectively reduce cardiovascular risk and improve mental health and HIV outcomes than standard psychoeducation, and to explore how HOPE works to produce these changes. The research is designed to provide practical, scalable strategies that clinics can use to support aging people living with HIV.

Why it matters

Potential benefit: If successful, HOPE could help older adults with HIV stay healthier with better heart and mental health.

How similar studies have gone: Previous health-promotion and psychoeducation approaches have shown benefits in related populations, but this study tests a tailored HOPE program for older adults with HIV.

Where this research is happening

  • University of Miami School of Medicine
    Coral Gables, United States
    Active

Researchers

  • Principal investigator: Jimenez, Daniel Enrique — University of Miami School of Medicine
  • Study coordinator: Jimenez, Daniel Enrique

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.