Home wearable movement monitoring for Ataxia-Telangiectasia
Official title: Development of Real-World Motor Outcome Measures in Ataxia-Telangiectasia
Funded at Massachusetts General Hospital · NIH-11239081 · Data updated 2026-11-12
This project uses small wearable sensors to track everyday movements in children and adults with Ataxia-Telangiectasia to spot meaningful changes in motor function.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | December 15, 2023 |
| Project end | November 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $624,776 |
| NIH project number | 5R01NS134597-03 |
| Project ID | NIH-11239081 on NIH RePORTER |
Who could benefit from this research
✓Could help
People diagnosed with Ataxia-Telangiectasia, including children (around age 6 and older) and adults, who can wear a wrist or ankle sensor at home and whose caregivers can assist if needed.
✕Less likely to help
Individuals without Ataxia-Telangiectasia or those unable to wear or comply with continuous home sensor monitoring are unlikely to benefit directly from participating.
What this research studies
You would wear a small, consumer-grade sensor on your wrist or ankle that collects movement data passively at home. Researchers will apply signal-processing and machine-learning methods to identify basic movement building blocks called “submovements” from the continuous data. Those sensor-derived features will be compared with clinician exams and caregiver reports to make measures that are reliable, interpretable, and sensitive to daily fluctuations and disease progression. The goal is to create real-world motor measures that can support care and help future clinical trials.
Why it matters
Potential benefit: If successful, this work could give patients and clinicians a sensitive, real-world way to monitor motor changes and detect treatment effects earlier.
How similar studies have gone: Preliminary pilot work from the team shows these sensor features are reliable and correlate with clinician and caregiver ratings, but larger validation is still needed.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Gupta, Anoopum Satyawan — Massachusetts General Hospital
- Study coordinator: Gupta, Anoopum Satyawan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.