Home monitoring for dangerous metabolic buildups
Home Monitoring of Metabolic Disorders
A small at-home device that lets people with certain metabolic conditions check a key blood chemical each morning to catch rising levels before a crisis.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sequitur Health Corp. NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project ID | NIH-11182502 on NIH RePORTER |
What this research studies
You would use a handheld device that measures a specific metabolite from a single drop of blood taken at home, typically in the morning before eating. Participants will take daily fasting measurements and the study will track whether high readings lead them or their caregivers to contact their medical team or change care. The device has been developed and partly validated in labs and through prior funding, and this work brings the device into real-world home use for the first time in the target patient group. The team is also working toward FDA clearance as part of the device development pathway.
Who could benefit from this research
Good fit: People of any age who have metabolic disorders that cause buildup of the targeted metabolite and who or whose caregivers can perform simple fingerstick blood tests at home would be ideal candidates.
Not a fit: People without the specific metabolic disorder, those who cannot perform fingerstick testing, or those without access to follow-up medical care may not gain benefit from this device.
Why it matters
Potential benefit: If successful, this could let people and caregivers detect dangerous metabolite rises earlier and prompt timely medical action to reduce crises.
How similar studies have performed: Related devices have been developed and validated in laboratory settings and through prior SBIR funding, but this is the first time the device will be used daily at home in the intended patient population.
Where this research is happening
Scottsdale, United States
- Sequitur Health Corp. — Scottsdale, United States (Active)
Researchers
- Principal investigator: Thomas, Marylaura Lind — Sequitur Health Corp.
- Study coordinator: Thomas, Marylaura Lind
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.