Home HPV self-sampling with supportive 3R counseling for women with HIV in Ghana

The Impact of an Evidence-Based, Behavioral Cervical Cancer Screening Intervention among Women Living with HIV in Ghana (HOPE-inG): A Type 2 Hybrid Effectiveness Implementation Trial

NIH-funded research Baylor University · NIH-11398288

This project offers HPV self-sampling plus a brief 3R communication approach to help women living with HIV in Ghana get timely cervical cancer screening.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionBaylor University NIH-funded
Lab location1 site (Waco, United States)
Project IDNIH-11398288 on NIH RePORTER

What this research studies

You would be offered a HPV self-sampling kit to use at home together with a short, supportive communication session using a Reframing-Reprioritizing-Reforming (3R) approach. Women receiving HOPE will be compared with those getting routine clinic-based screening at selected secondary-level health facilities. The team will work with four hospitals to adapt and test strategies that help clinics adopt and keep offering the self-sampling approach. The trial measures both how well the approach gets patients screened and how to make it part of regular care.

Who could benefit from this research

Good fit: Women living with HIV who are eligible for cervical cancer screening and receive care at participating secondary-level health facilities in Ghana are the ideal candidates.

Not a fit: People who are not living with HIV, not eligible for cervical screening, already up-to-date on screening, or living outside the participating Ghana clinics are unlikely to benefit from joining this project.

Why it matters

Potential benefit: If successful, this could make screening easier to access and substantially increase early detection of cervical pre-cancer and cancer among women with HIV.

How similar studies have performed: A previous randomized trial in Ghana showed the HOPE approach greatly increased screening uptake compared with routine clinic screening, though larger-scale implementation has not yet been tested.

Where this research is happening

Waco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.