Home HPV self-sampling with supportive 3R counseling for women with HIV in Ghana
Official title: The Impact of an Evidence-Based, Behavioral Cervical Cancer Screening Intervention among Women Living with HIV in Ghana (HOPE-inG): A Type 2 Hybrid Effectiveness Implementation Trial
Funded at Baylor University · NIH-11398288 · Data updated 2026-11-12
This project offers HPV self-sampling plus a brief 3R communication approach to help women living with HIV in Ghana get timely cervical cancer screening.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor University NIH-funded |
| Lab location | 1 site (Waco, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $164,797 |
| NIH project number | 3U01CA294757-02S1 |
| Project ID | NIH-11398288 on NIH RePORTER |
Who could benefit from this research
✓Could help
Women living with HIV who are eligible for cervical cancer screening and receive care at participating secondary-level health facilities in Ghana are the ideal candidates.
✕Less likely to help
People who are not living with HIV, not eligible for cervical screening, already up-to-date on screening, or living outside the participating Ghana clinics are unlikely to benefit from joining this project.
What this research studies
You would be offered a HPV self-sampling kit to use at home together with a short, supportive communication session using a Reframing-Reprioritizing-Reforming (3R) approach. Women receiving HOPE will be compared with those getting routine clinic-based screening at selected secondary-level health facilities. The team will work with four hospitals to adapt and test strategies that help clinics adopt and keep offering the self-sampling approach. The trial measures both how well the approach gets patients screened and how to make it part of regular care.
Why it matters
Potential benefit: If successful, this could make screening easier to access and substantially increase early detection of cervical pre-cancer and cancer among women with HIV.
How similar studies have gone: A previous randomized trial in Ghana showed the HOPE approach greatly increased screening uptake compared with routine clinic screening, though larger-scale implementation has not yet been tested.
Where this research is happening
-
Baylor University
Waco, United States Active
Researchers
- Principal investigator: Asare, Matthew — Baylor University
- Study coordinator: Asare, Matthew
Related research
Other NIH-funded projects on the same topics.
-
mSaada: a mobile tool to boost cervical cancer screening in western Kenya
A mobile app helps community health volunteers manage cervical cancer screening tasks and follow-up for women in low-resource areas.
-
HPV self-collection in HIV care to screen for cervical cancer in Ethiopia
A patient-centered program tests a simple HPV self-collection approach within HIV clinics in Ethiopia to help detect cervical cancer earlier.
-
HOPE-inG: Increasing cervical cancer screening for women with HIV in Ghana
A study tests a home-based HPV self-sampling approach plus a tailored communication plan to help women living with HIV in Ghana get screened more often for cervical cancer.
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CODA-based cervical cancer screening for LMICs using CRISPR and fluorescence
A low-resource, rapid test called CODA uses CRISPR and light signals to detect cervical cancer markers in women in sub-Saharan Africa to improve screening.
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CODA-based cervical cancer screening in low-resource settings
A new, quick, low-cost test using CRISPR and fluorescence readouts to help screen for cervical cancer in women in sub-Saharan Africa.
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CATSystem: a digital tool to boost cervical cancer screening and follow-up in Kenya
A digital tracking system helps doctors and patients in Kenya improve cervical cancer screening, treatment referrals, and follow-up, especially for women living with HIV.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.