Home exercise program with a mobile app after LVAD (HeartMate 3)

Home-based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation

NIH-funded research University of Pennsylvania · NIH-11134612

This project offers a home walking and strengthening program delivered through a mobile app for people who have received a HeartMate 3 left ventricular assist device to help increase daily activity and muscle strength.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11134612 on NIH RePORTER

What this research studies

You would use a phone app and wearable activity tracking to follow a structured walking and resistance program at home after your LVAD surgery. The project is a randomized, controlled pilot where some participants follow the mobile home program while others receive usual care, with exercise prescriptions and progression guided by collected activity data. Outcomes include daily steps, six-minute walk distance, measures of muscle strength/quantity, and frailty-related measures, collected over months after implantation. The goal is to start rehabilitation earlier than typical center-based programs and make exercise easier to do from home.

Who could benefit from this research

Good fit: Ideal candidates are adults who have received a HeartMate 3 LVAD and are medically stable after discharge but want to begin home-based cardiac rehabilitation.

Not a fit: People who are medically unstable after LVAD surgery, have device complications, cannot safely exercise, or cannot use a smartphone/wearable may not benefit from this program.

Why it matters

Potential benefit: If successful, the program could help LVAD recipients walk more, gain strength, reduce frailty, and possibly lower healthcare use.

How similar studies have performed: Center-based cardiac rehabilitation and exercise programs have helped many heart failure patients, but home-based mobile rehabilitation specifically for LVAD recipients is relatively new and supported mainly by early or pilot studies.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.