NIH-funded research NIH-funded research

Home-based therapy for managing phantom limb pain in Veterans with amputations

Official title: Home-based rehabilitation intervention for phantom limb pain in Veterans with lower limb amputations

Funded at Minneapolis VA Medical Center · NIH-11010375 · Data updated 2026-11-12

This study is creating a friendly mobile app to help Veterans with lower limb amputations manage phantom limb pain using fun exercises that train the brain, and we want to hear from them to make sure the app works well for their needs.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMinneapolis VA Medical Center
NIH-funded
Lab location1 site (Minneapolis, United States)
Project startApril 1, 2024
Project endMarch 31, 2029
Funding year2025
NIH project number5IK2RX004805-02
Project IDNIH-11010375 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are Veterans with lower limb amputations who experience moderate to severe phantom limb pain.

Less likely to help

Patients who do not have lower limb amputations or do not experience phantom limb pain may not benefit from this research.

What this research studies

This research focuses on developing a mobile app to help Veterans with lower limb amputations manage phantom limb pain (PLP) through a technique called graded motor imagery (GMI). The approach involves training the brain to recognize the missing limb through exercises that include limb laterality training, motor imagery, and mirror therapy. Veterans will participate in interviews to provide feedback on the app, which will be refined based on their experiences to ensure it meets their needs. The goal is to create an effective, user-friendly tool that can be used at home to alleviate pain and improve rehabilitation outcomes.

Why it matters

Potential benefit: If successful, this research could provide Veterans with a convenient and effective way to manage phantom limb pain, enhancing their quality of life and rehabilitation success.

How similar studies have gone: Previous research has shown promise in using graded motor imagery techniques for pain management, indicating potential success for this novel application in a mobile format.

Where this research is happening

  • Minneapolis VA Medical Center
    Minneapolis, United States
    Active

Researchers

  • Principal investigator: Rich, Tonya L — Minneapolis VA Medical Center
  • Study coordinator: Rich, Tonya L

Related research

Other NIH-funded projects on the same topics.

  • Home brain stimulation plus guided touch for phantom limb pain

    This project sees if a portable brain stimulation device combined with guided touch exercises can lower phantom limb pain for people who have lost a limb.

    NIH research Spaulding Rehabilitation Hospital · Charlestown, United States · NIH-11321673

  • Home-based rehabilitation for phantom limb pain using a mobile app

    A mobile app offers guided graded motor imagery exercises to help Veterans with lower-limb amputations manage phantom limb pain at home.

    NIH research Minneapolis VA Medical Center · Minneapolis, United States · NIH-11310743

  • Understanding what causes phantom limb pain after amputation

    This study is looking at what causes phantom limb pain in people who have had an amputation, and it involves talking to those individuals to better understand their experiences and gather real-time feedback to help create more personalized treatments.

    NIH research University of Minnesota · Minneapolis, United States · NIH-10922729

  • Training the brain to reduce phantom limb pain

    This study is testing a new, gentle therapy to help people who have lost a limb feel less phantom limb pain by training their brains to better process sensations.

    NIH research Stratton Veterans Admin Medical Center · Albany, United States · NIH-10851754

  • Neuropathic pain after childhood amputation

    This project sees how common phantom and residual limb neuropathic pain is and how it affects children and teens who had limb amputations.

    Recruiting Hopitaux de Saint-Maurice · Saint-Maurice · NCT07401966

  • Effects of magnetic stimulation on phantom limb pain in amputees

    This study tests if using magnetic stimulation can help reduce phantom limb pain in people who have had upper limb amputations.

    Recruiting Skolkovo Institute of Science and Technology · Moscow · NCT06813937

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.