Home-based long-acting HIV injections by trained caregivers
RFA-PS-23-004, Innovative Administration of Long-Acting Injectables for HIV Treatment Enhancement at Home (INVITE-Home)
This project tries giving long-acting HIV injections at home by trained family members or friends for people living with HIV to make treatment more private and easier to keep up with.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11129590 on NIH RePORTER |
What this research studies
If you live with HIV and are interested in long-acting injectable ART, this project offers training and support so a trusted layperson (like a family member, friend, or partner) can give injections at home. The team will follow how comfortable and confident patients and lay injectors feel, whether injections happen on schedule, and whether this reduces travel, stigma, and missed doses. Researchers will collect patient and clinician feedback and track care engagement and treatment persistence to see how well the home model works. The goal is to make long-acting HIV treatment more convenient, private, and accessible.
Who could benefit from this research
Good fit: Ideal candidates are people living with HIV who are eligible for long-acting injectable ART and who have a willing, trusted person who can be trained to give injections at home.
Not a fit: People who cannot find a trusted layperson to administer injections, who are medically ineligible for LAI-ART, or who prefer and can access clinic-based care may not benefit from this approach.
Why it matters
Potential benefit: If successful, this could let more people stay on long-acting HIV treatment by making injections more convenient, private, and easier to access.
How similar studies have performed: Layperson or caregiver administration of injections has worked in other medical contexts, but using this model for long-acting HIV treatment is new and has not been tested yet.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Saberi, Parya — University of California, San Francisco
- Study coordinator: Saberi, Parya
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.