Home-based high-intensity interval training to reduce frailty in older veterans

High Intensity Interval Training (HIIT) to Reduce Frailty and Enhance Resilience in Older Veterans

['FUNDING_OTHER'] · KANSAS CITY VA MEDICAL CENTER · NIH-11360817

This program tests whether a short, home-based high-intensity interval training (HIIT) routine can help older U.S. veterans become stronger, more resilient, and less likely to become frail.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorKANSAS CITY VA MEDICAL CENTER (nih funded)
Locations1 site (KANSAS CITY, UNITED STATES)
Trial IDNIH-11360817 on ClinicalTrials.gov

What this research studies

If I join, I'll follow a tailored 12-week HIIT exercise plan I can do at home with regular check-ins from the VA team. The study team will measure my strength, balance, daily function, and some biological markers before and after the program to see if I recover better from stress and avoid frailty. Wearable monitors and a few clinic visits for testing or sample collection may be required. Researchers will compare results across participants to learn who benefits most and which signs of resilience change.

Who could benefit from this research

Good fit: Ideal participants are U.S. veterans aged 65 or older who are medically stable but show early signs of frailty or reduced physical resilience and can safely perform moderate-to-high intensity home exercise.

Not a fit: People with unstable cardiovascular disease, severe mobility impairments, or other medical conditions that make high-intensity exercise unsafe would likely not benefit and may be excluded.

Why it matters

Potential benefit: If successful, this could help older veterans regain strength and recover more quickly from illness or falls, reducing disability and hospital stays.

How similar studies have performed: A prior VA pilot showed 12 weeks of HIIT is feasible in older veterans and HIIT has improved fitness in other older adult studies, but its effect specifically on frailty and resilience is still being studied.

Where this research is happening

KANSAS CITY, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.