Home-based follow-up and nutritional support for adults with HIV after hospital discharge
HomeLink2: Reducing posthospitalization mortality among people living with HIV through structured home care and nutritional supplementation
This project compares usual care to structured home visits, with or without nutritional supplements, to help adults with HIV survive the months after leaving the hospital.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11182732 on NIH RePORTER |
What this research studies
If I join, the program will offer structured home visits after I leave the hospital that include psychosocial counseling and linkages to care. Some participants will also receive nutritional supplements during those visits. The study will compare outcomes for people who get usual care, home visits alone, or home visits plus nutrition to see which approach most reduces deaths after discharge. The team will also look at why the approach works by tracking things like timely access to acute care, medical diagnoses made after discharge, and staying on HIV treatment.
Who could benefit from this research
Good fit: Adults living with HIV who were recently hospitalized and are being discharged in participating sites (primarily in South Africa) are the ideal candidates.
Not a fit: People who are not living with HIV, children, or adults who were not recently hospitalized are unlikely to benefit from this specific intervention.
Why it matters
Potential benefit: If successful, this approach could substantially lower the risk of death in the months after hospital discharge for people living with HIV.
How similar studies have performed: A prior pilot of the HomeLink intervention showed a large benefit, reducing posthospital mortality by about 60%, so this trial builds on promising earlier results.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Hoffmann, Christopher J — Johns Hopkins University
- Study coordinator: Hoffmann, Christopher J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.