Home air and dust's role in peanut allergy in babies
Role of the indoor exposome in peanut allergy development
Researchers are looking at whether things in household dust and indoor air help cause peanut allergy in infants and young children.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11239803 on NIH RePORTER |
What this research studies
If you join, the project will look at whether things in your home's dust and indoor air help cause peanut allergy in babies. Researchers combine experiments in mice that mimic breathing in peanut plus dust with a study of infants where they collect home dust samples and test babies for signs of peanut sensitization. They will measure tiny particles, air pollutants, and immune-stimulating components in dust, and compare those exposures with blood or skin tests for peanut allergy in infants. Lab studies will also try to show how these household exposures change the immune system to cause allergies.
Who could benefit from this research
Good fit: Ideal candidates would be families with infants or very young children willing to provide home dust samples and allow allergy testing of their baby.
Not a fit: People who already have an established peanut allergy or older children and adults are unlikely to receive direct benefit from participating.
Why it matters
Potential benefit: If successful, this work could point to household triggers to avoid and new ways to prevent peanut allergy in young children.
How similar studies have performed: Previous animal studies have shown that co-exposure to peanut and indoor dust or pollutants can cause peanut allergy, while human evidence is still limited and being developed.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Moran, Timothy — Univ of North Carolina Chapel Hill
- Study coordinator: Moran, Timothy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.