HIV treatment, vaccine, and prevention trials at the University of Pennsylvania

University of Pennsylvania HIV Clinical Trials Unit

NIH-funded research University of Pennsylvania · NIH-11238421

Penn runs clinical trials testing new HIV treatments, vaccines, and prevention methods for adults living with or at risk for HIV.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11238421 on NIH RePORTER

What this research studies

At Penn you can join trials run at two clinic sites that offer treatment, vaccine, and prevention studies run through national HIV research networks (ACTG, HVTN, HPTN). If you enroll, you would have scheduled clinic visits, blood tests, possible medication or vaccine doses, and follow-up to track safety and outcomes. The Penn team works with national networks and local community groups to make trials accessible and to include newer investigators in study care.

Who could benefit from this research

Good fit: Adults (typically age 21 and older) living with HIV or at increased risk for HIV who can attend regular clinic visits and follow study procedures are typical candidates.

Not a fit: People under 21, those who are pregnant or who cannot meet specific trial eligibility or visit requirements may not be able to join or receive direct benefit from these trials.

Why it matters

Potential benefit: Successful trials could lead to better HIV treatments, vaccines, and prevention tools that reduce illness and transmission for people with or at risk for HIV.

How similar studies have performed: Previous ACTG, HVTN, and HPTN trials have produced major advances in HIV treatment and prevention (for example antiretroviral therapy and PrEP), while vaccine development has had mixed results and remains an active research area.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.