HIV treatment and vaccine partnership across Cleveland, Cincinnati, and Kampala
Case Clinical Trials Unit
This program runs clinical trials testing treatments, vaccines, and cure approaches for adults living with or at risk for HIV.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-11237593 on NIH RePORTER |
What this research studies
This program runs clinical trials at three clinical sites in Cleveland, Cincinnati, and Kampala that offer treatment, vaccine, and cure-focused studies for people affected by HIV. It links hands-on patient visits with laboratory work to monitor immune responses and study co-infections like tuberculosis and hepatitis. The teams work within the ACTG and HVTN networks and aim to enroll adults from diverse and hard-to-reach communities. If I qualify, I could join a trial, provide blood or other samples, and have regular clinic visits to track safety and effectiveness.
Who could benefit from this research
Good fit: Adults (commonly 21 years and older) living with HIV or at high risk for HIV, including those with TB or hepatitis co-infections, are typical candidates for these trials.
Not a fit: Children under the typical adult age limits and people who do not meet specific trial eligibility (or cannot attend required site visits) likely would not be able to participate or benefit directly.
Why it matters
Potential benefit: If successful, the program could produce better HIV treatments, more effective vaccines, and progress toward strategies for long-term remission or cure.
How similar studies have performed: Previous ACTG and HVTN trials have produced major advances in antiretroviral therapy and HIV prevention, while vaccine and cure strategies remain an active and partly experimental area of research.
Where this research is happening
Cleveland, United States
- Case Western Reserve University — Cleveland, United States (Active)
Researchers
- Principal investigator: Yendewa, George — Case Western Reserve University
- Study coordinator: Yendewa, George
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.