HIV prevention offered during household visits for people affected by TB

TB PrEP - Integrating HIV prevention with TB household contact evaluation

NIH-funded research University of Washington · NIH-11411581

This project brings HIV prevention pills (PrEP) to people who live with someone who has tuberculosis to help prevent HIV infection.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Washington NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-11411581 on NIH RePORTER

What this research studies

You would be offered an HIV test during a home visit when someone in your household is being treated for tuberculosis, and if you are HIV-negative staff would offer PrEP pills, counseling, and help linking to follow-up care. The team adapts a proven PrEP delivery approach to fit TB household contact visits and provides support to start and continue the medication. Study staff will track who accepts PrEP, how well people stay on it, and connections to local health services over time. The work focuses on high HIV/TB burden settings such as Uganda where people in TB-affected households face higher HIV risk.

Who could benefit from this research

Good fit: People who live in the same household as someone being treated for tuberculosis, are HIV-negative, and are willing to consider taking PrEP (typically adults and older adolescents).

Not a fit: People who are already living with HIV, who cannot take PrEP for medical reasons, or who do not live in TB-affected households are unlikely to benefit from this program.

Why it matters

Potential benefit: If successful, this could increase access to PrEP for household members of TB patients and reduce new HIV infections.

How similar studies have performed: Other programs have successfully delivered PrEP through household- or couple-based approaches in high HIV-burden settings, so this adapts a proven method to TB contact visits.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.