HIV prevention network coordinating center

HIV Prevention Trials Network Leadership and Operations Center

['FUNDING_OTHER'] · FAMILY HEALTH INTERNATIONAL · NIH-11466551

This program runs and supports studies of new long-acting HIV prevention medicines and combined products for people at risk, including young adults, men who have sex with men, transgender women, sex workers, and people who inject drugs.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorFAMILY HEALTH INTERNATIONAL (nih funded)
Locations1 site (DURHAM, UNITED STATES)
Trial IDNIH-11466551 on ClinicalTrials.gov

What this research studies

From a patient perspective, this program designs and runs clinical studies to find HIV prevention options that are safe, acceptable, and easy to use. It focuses on long-acting antiretroviral approaches for PrEP, multipurpose products that may also prevent pregnancy or other STIs, and antibody-based strategies. The network works with clinical sites in the U.S. and around the world, including sub-Saharan Africa, and partners with other HIV research groups. If invited, you would visit a participating clinic where staff would explain the prevention product, study procedures, and safety monitoring.

Who could benefit from this research

Good fit: Ideal participants are HIV-negative people at higher risk for HIV—for example sexually active young adults, men who have sex with men, transgender women, female sex workers, people who inject drugs, and women in high-incidence regions—who can attend a participating clinic.

Not a fit: People already living with HIV or those not at risk for HIV are not the primary focus and are unlikely to benefit from these prevention studies.

Why it matters

Potential benefit: If successful, the work could deliver longer-lasting, more convenient HIV prevention options and combined products that reduce HIV and other risks.

How similar studies have performed: Earlier prevention efforts like daily oral PrEP and long-acting injectable cabotegravir have shown clear protection, while multipurpose products and some antibody approaches are newer and less proven.

Where this research is happening

DURHAM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.