HIV drug resistance in the new ART era in Kenya
Official title: HIV Drug Resistance in the New Antiretroviral Therapy Era in Kenya
Funded at Miriam Hospital · NIH-11614276 · Data updated 2026-11-12
This project looks at how HIV drug resistance develops and is managed in Kenya as newer HIV medicines become common.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Miriam Hospital NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project start | September 12, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $185,269 |
| NIH project number | 3R01AI186632-03S1 |
| Project ID | NIH-11614276 on NIH RePORTER |
Who could benefit from this research
✓Could help
People living with HIV in Kenya and similar resource-limited settings who are on antiretroviral therapy and may experience treatment failure or resistance.
✕Less likely to help
Patients in non-resource-limited settings with robust monitoring may not see direct changes from this study.
What this research studies
The grant focuses on understanding HIV drug resistance patterns in resource-limited settings where monitoring may be limited. It considers how modern therapies like dolutegravir change resistance dynamics and patient outcomes. Researchers plan to analyze data on treatment histories, viral load results, and resistance testing to inform better care in real-world clinics.
Why it matters
Potential benefit: Better guidance for selecting treatments and monitoring strategies to prevent or manage resistance in people living with HIV.
How similar studies have gone: Previous work has shown that resistance patterns can shift with new ART drugs, but data remain limited in low-resource settings, making this both important and potentially practice-changing.
Where this research is happening
-
Miriam Hospital
Providence, United States Active
Researchers
- Principal investigator: Kantor, Rami — Miriam Hospital
- Study coordinator: Kantor, Rami
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.