HIV data and analysis hub
Official title: Core-001
Funded at University of California at Davis · NIH-11530311 · Data updated 2026-11-12
This project builds a secure online library and analysis service to help researchers link HIV vaccine and clinical data so they can learn how vaccines affect T-cell responses and viral control in people with HIV.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | May 22, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $323,834 |
| NIH project number | 5P01AI178375-04 |
| Project ID | NIH-11530311 on NIH RePORTER |
Who could benefit from this research
✓Could help
People with HIV who enroll in OmiT-HIV vaccine studies or agree to donate clinical samples and de-identified data to participating projects are the ideal candidates for this work.
✕Less likely to help
Healthy people without HIV and people with HIV who are not enrolled in OmiT-HIV projects or who do not contribute data or samples would not directly benefit from this core.
What this research studies
We will create and maintain a secure UCSF Data Library space to store de-identified clinical information and high-dimensional laboratory data from the OmiT-HIV program. The core team will provide biostatistics and bioinformatics support and run integrated analyses that combine immune measures, metabolic data, and viral outcomes. Project teams across sites will upload data using shared formats so information stays organized and can be shared safely among collaborators. By connecting lab results and patient data, the work aims to speed understanding of how vaccine approaches and metabolic health influence immune responses and virus control.
Why it matters
Potential benefit: If successful, this could speed discovery of vaccine strategies that improve T-cell responses and viral control for people living with HIV.
How similar studies have gone: Data-sharing platforms and multi-omics integration have helped find immune markers in prior HIV research, but applying unified cross-species, multi-modal analyses to therapeutic vaccine responses is a newer approach.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Hartigan-O'connor, Dennis J. — University of California at Davis
- Study coordinator: Hartigan-O'connor, Dennis J.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.