NIH-funded research NIH-funded research

HIV clinical trials unit serving Cleveland, Cincinnati, and Kampala

Official title: Case Clinical Trials Unit

Funded at Case Western Reserve University · NIH-11456877 · Data updated 2026-11-12

This program runs HIV treatment, vaccine, and related studies for adults living with or at risk for HIV.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionCase Western Reserve University
NIH-funded
Lab location1 site (Cleveland, United States)
Project startFebruary 13, 2007
Project endNovember 30, 2027
Funding year2026
Award (this year)$479,119
NIH project number3UM1AI069501-20S1
Project IDNIH-11456877 on NIH RePORTER

Who could benefit from this research

Could help

Adults (typically 21 years and older) living with HIV or at risk for HIV who can attend visits at one of the participating sites are the usual candidates.

Less likely to help

Children under site age cutoffs, people unable to travel to the listed locations, or those who do not meet specific study eligibility rules may not benefit or be eligible.

What this research studies

This multi-site clinical research unit brings together Case Western Reserve, the University of Cincinnati, and the Joint Clinical Research Center in Kampala to run HIV treatment and prevention studies. You might be invited to join trials of antiretroviral drugs, vaccine studies, or research on HIV-related conditions like tuberculosis, hepatitis, and inflammation. Staff link clinic work with laboratory testing, including immune monitoring and translational science, and they enroll people from diverse and hard-to-reach communities. If you participate, you would follow study visits at one of the sites and may provide samples or clinical data for the research.

Why it matters

Potential benefit: If successful, the program could improve HIV treatments, prevention tools, and advance efforts toward cure and better management of co-infections.

How similar studies have gone: Groups like the ACTG and HVTN have produced many important HIV treatment and prevention advances, though cure and some vaccine approaches remain experimental.

Where this research is happening

  • Case Western Reserve University
    Cleveland, United States
    Active

Researchers

  • Principal investigator: Yendewa, George — Case Western Reserve University
  • Study coordinator: Yendewa, George

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.