High-Speed X-ray Angiography for Heart Procedures
Official title: High Speed 1000 fps Angiography for X-ray Image Guided Cardiovascular Interventions
Funded at State University of New York at Buffalo · NIH-11485394 · Data updated 2026-11-12
A new HSAngio imaging system aims to help doctors see blood flow during heart procedures without changing current X-ray machines.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Buffalo NIH-funded |
| Lab location | 1 site (Amherst, United States) |
| Project start | September 5, 2026 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $600,657 |
| NIH project number | 1R01EB040435-01 |
| Project ID | NIH-11485394 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients undergoing cardiovascular interventional procedures who would benefit from enhanced real-time imaging.
✕Less likely to help
Patients not undergoing interventional imaging or those with contraindications to iodinated contrast may not benefit.
What this research studies
This project seeks to create a high-speed (1000 fps) angiography method that works with existing X-ray generators to better visualize blood flow during cardiovascular interventions. It includes a fast iodine contrast delivery system, synchronization of image capture with the heart’s diastole, and noise-reduction algorithms to improve image clarity in the chest. A tracking feature will monitor radiation dose to keep patient and staff exposure safe. The work will build on prior efforts in brain aneurysm care and expand into ischemic heart disease procedures using 3D-printed vascular models for testing.
Why it matters
Potential benefit: If successful, this technology could provide sharper, real-time images during heart interventions, potentially improving accuracy and outcomes.
How similar studies have gone: Previous development in HSAngio for brain aneurysm care shows promise, suggesting potential for cardiovascular use with further refinement.
Where this research is happening
-
State University of New York at Buffalo
Amherst, United States Active
Researchers
- Principal investigator: Setlur Nagesh, Swetadri Vasan — State University of New York at Buffalo
- Study coordinator: Setlur Nagesh, Swetadri Vasan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.