High-resolution ultrasound for guiding minimally invasive procedures

High Resolution Ultrasound in Interventional Radiology

NIH-funded research Stanford University · NIH-11286797

Using a new real-time ultrasound device to help doctors guide biopsies and ablations in adults without radiation or iodinated contrast.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-11286797 on NIH RePORTER

What this research studies

This project aims to build a new high-resolution real-time ultrasound that lets doctors watch needles and ablations in 3D without radiation or contrast. The team will create a wide 2D transducer made of tiled modules, image multiple adjacent planes to visualize instruments, and use fast plane-wave transmissions to produce about 30 volumetric updates per second. They will add software for aberration correction and implement B-Mode, color Doppler, volumetric flow, and contrast imaging to show anatomy and blood flow. The work will move from device and algorithm development toward use in adult abdominal image-guided procedures.

Who could benefit from this research

Good fit: Adults (21+) who are scheduled for or considering image-guided abdominal procedures such as biopsies, tumor ablations, or other minimally invasive interventions.

Not a fit: People under 21, patients whose procedures do not use ultrasound guidance, or those who specifically need CT-based imaging details are unlikely to benefit directly.

Why it matters

Potential benefit: If successful, this could let clinicians target biopsies and ablations more precisely and safely while avoiding ionizing radiation and iodinated contrast.

How similar studies have performed: Prior work has improved ultrasound resolution and plane-wave imaging, but this particular integrated high-resolution volumetric approach is relatively novel and not yet widely tested in patients.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.