High-resolution imaging of the cornea

Wide-field three-dimensional high-resolution imaging of the cornea

['FUNDING_R21'] · UNIVERSITY OF COLORADO · NIH-11039759

This study is working on a new way to take clear pictures of the tiny details in the cornea, which is the front part of your eye, to help doctors better diagnose and treat eye problems that could cause vision loss.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF COLORADO (nih funded)
Locations1 site (Boulder, UNITED STATES)
Trial IDNIH-11039759 on ClinicalTrials.gov

What this research studies

This research aims to develop a new imaging technique that allows for detailed visualization of the cornea's fine structures in living patients. By utilizing advanced methods like speckle illumination holographic imaging, the project seeks to overcome current limitations in corneal imaging, such as the need for physical contact and small field-of-view. The goal is to create a user-friendly imaging system that can be easily implemented in clinical settings, providing better diagnostic capabilities for corneal disorders. This could significantly enhance the ability to assess and manage conditions that lead to blindness.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals over 21 years old who are experiencing corneal disorders.

Not a fit: Patients with no corneal issues or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnosis and treatment of corneal disorders, potentially reducing the risk of blindness.

How similar studies have performed: While there have been advancements in imaging technologies like optical coherence tomography, this specific approach is novel and aims to address existing challenges in corneal imaging.

Where this research is happening

Boulder, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.