High-intensity exercise to improve brain and blood vessel health in older adults with HIV.

A Pilot Trial of High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Older Adults with HIV.

NIH-funded research University of Alabama at Birmingham · NIH-11001585

This study is looking at how high-intensity exercise can help older adults with HIV who are having trouble with thinking and blood vessel health, and it aims to see if working out can make their minds and arteries feel better.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-11001585 on NIH RePORTER

What this research studies

This research investigates how high-intensity exercise can help older adults living with HIV who are experiencing cognitive decline and vascular issues. The study aims to assess the effects of exercise on arterial stiffness and cognitive function, which are critical factors in the health of this vulnerable population. Participants will engage in structured exercise programs designed to enhance their vascular health and potentially improve cognitive outcomes. The research is led by an experienced exercise physiologist focused on aging and vascular health.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults living with HIV who are experiencing cognitive decline or neurocognitive disorders.

Not a fit: Patients who are not living with HIV or who do not have cognitive impairments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective non-drug interventions that improve cognitive function and vascular health in older adults with HIV.

How similar studies have performed: Previous research has shown that exercise can positively impact cognitive function and vascular health in various populations, suggesting potential success for this approach in older adults with HIV.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virusage associated diseaseage associated disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.