High-intensity exercise to improve brain and blood vessel health in older adults with HIV.
Official title: A Pilot Trial of High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Older Adults with HIV.
Funded at University of Alabama at Birmingham · NIH-11001585 · Data updated 2026-11-12
This study is looking at how high-intensity exercise can help older adults with HIV who are having trouble with thinking and blood vessel health, and it aims to see if working out can make their minds and arteries feel better.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project start | January 1, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $125,982 |
| NIH project number | 5K01AG086063-02 |
| Project ID | NIH-11001585 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults living with HIV who are experiencing cognitive decline or neurocognitive disorders.
✕Less likely to help
Patients who are not living with HIV or who do not have cognitive impairments may not benefit from this research.
What this research studies
This research investigates how high-intensity exercise can help older adults living with HIV who are experiencing cognitive decline and vascular issues. The study aims to assess the effects of exercise on arterial stiffness and cognitive function, which are critical factors in the health of this vulnerable population. Participants will engage in structured exercise programs designed to enhance their vascular health and potentially improve cognitive outcomes. The research is led by an experienced exercise physiologist focused on aging and vascular health.
Why it matters
Potential benefit: If successful, this research could lead to effective non-drug interventions that improve cognitive function and vascular health in older adults with HIV.
How similar studies have gone: Previous research has shown that exercise can positively impact cognitive function and vascular health in various populations, suggesting potential success for this approach in older adults with HIV.
Where this research is happening
-
University of Alabama at Birmingham
Birmingham, United States Active
Researchers
- Principal investigator: Jones, Raymond — University of Alabama at Birmingham
- Study coordinator: Jones, Raymond
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.