High-density silicon carbide brain electrode arrays for long-lasting neural recording

Scalable fabrication of high-density amorphous silicon carbide microelectrode arrays for chronic neural interfacing

NIH-funded research University of Oregon · NIH-11146571

They are developing tiny, durable brain electrodes to capture high-quality neural signals for people who need long-term brain monitoring or brain–computer interfaces.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Oregon NIH-funded
Lab location1 site (Eugene, United States)
Project IDNIH-11146571 on NIH RePORTER

What this research studies

Researchers will use standard thin-film manufacturing to build 128-channel, ultra-microelectrode arrays from amorphous silicon carbide that are small enough to insert into the brain without complex implantation tools. The devices are designed with ultra-thin shanks and high channel density to reduce immune response and keep recording quality high for much longer than current implants. The project aims to match the signal quality of carbon-fiber electrodes while enabling scalable production so these devices can be used more widely in clinical and research settings. Early testing will focus on device fabrication and durability, with preclinical studies to evaluate tissue response and recording longevity before any human implants.

Who could benefit from this research

Good fit: Ideal candidates for future clinical use would be people who need chronic intracortical monitoring or brain–computer interfaces, such as individuals with paralysis, severe motor disorders, or those undergoing invasive epilepsy monitoring.

Not a fit: People who do not need brain implants, who can be cared for with noninvasive monitoring (like EEG), or who have medical contraindications to brain surgery are unlikely to benefit directly from this work in the near term.

Why it matters

Potential benefit: If successful, this could provide more reliable, longer-lasting brain recordings that improve neural prosthetics, monitoring, and treatments for neurological conditions.

How similar studies have performed: Carbon-fiber electrodes have produced excellent long-term recordings but are hard to scale up, and flexible thin-film devices have improved manufacturability though they have not yet matched carbon-fiber recording quality, so this project builds on both lines of work.

Where this research is happening

Eugene, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.