NIH-funded research U01 cooperative agreement

HFpEF: a diverse, real-world group to understand heart failure with preserved ejection fraction

Official title: A prospective multiethnic HFpEF cohort from Californias Central Valley

Funded at University of California at Davis · NIH-11531627 · Data updated 2026-11-12

A diverse group of people with HFpEF in California is being enrolled to learn more about the condition through detailed medical analyses.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of California at Davis
NIH-funded
Lab location1 site (Davis, United States)
Project startSeptember 10, 2021
Project endDecember 31, 2027
Funding year2026
Award (this year)$427,455
NIH project number3U01HL160274-05S2
Project IDNIH-11531627 on NIH RePORTER

Who could benefit from this research

Could help

Adults with HFpEF who are or could be enrolled in the HeartShare Registry across participating sites.

Less likely to help

Patients with HFpEF who are not enrolled in the registry or who do not consent to deep phenotyping may not directly benefit.

What this research studies

This project recruits HFpEF patients from UC Davis and other sites to build a large, multiethnic cohort for deep phenotyping. Researchers will enroll participants weekly and collect rich clinical data to understand how HFpEF manifests across different populations. The study also supports a HeartShare Registry, expanding opportunities for future research and patient involvement. Analyses will explore how organ systems interact and how treatments may affect clinically meaningful outcomes.

Why it matters

Potential benefit: If successful, findings could lead to more personalized care for HFpEF and better risk prediction across diverse groups.

How similar studies have gone: Previous HFpEF cohorts have shown that large, diverse datasets improve understanding of disease variability and treatment responses.

Where this research is happening

  • University of California at Davis
    Davis, United States
    Active

Researchers

  • Principal investigator: Chiamvimonvat, Nipavan — University of California at Davis
  • Study coordinator: Chiamvimonvat, Nipavan

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.