NIH-funded research NIH-funded research

Hepatitis B birth-dose vaccination: boosting uptake in Nigeria and beyond

Official title: Research Project 2

Funded at Washington University · NIH-11627094 · Data updated 2026-11-12

A national implementation project aims to speed up HepB birth-dose vaccination and protect newborns from liver cancer risk.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionWashington University
NIH-funded
Lab location1 site (Saint Louis, United States)
Project startSeptember 19, 2023
Project endAugust 31, 2028
Funding year2026
Award (this year)$37,500
NIH project number3U54CA284110-04S1
Project IDNIH-11627094 on NIH RePORTER

Who could benefit from this research

Could help

Newborns and their families in Nigeria and similar resource-limited settings where HepB birth-dose uptake is suboptimal.

Less likely to help

Hospitals or communities with high HepB birth-dose uptake and no barriers to vaccination may see limited additional benefit.

What this research studies

This project is centered on increasing timely HepB birth-dose vaccination for newborns in Nigeria and similar settings in Africa and the United States. It uses crowdsourcing to develop and test locally relevant messages and strategies to improve vaccine uptake outside hospital settings. The approach involves partnering with community clinics, birth sites, and outreach venues to implement effective vaccination campaigns and monitor progress over several years. The goal is to reduce hepatitis B transmission early in life and lower future liver-cancer risk by making the birth-dose more widely and quickly given. The study is designed to inform policy and practice through real-world implementation.

Why it matters

Potential benefit: If successful, more newborns will receive the HepB birth-dose on time, reducing HBV infection and future liver cancer risk.

How similar studies have gone: Prior use of crowdsourcing for health messaging has shown promise in improving vaccine uptake in similar settings, though this specific implementation is novel.

Where this research is happening

  • Washington University
    Saint Louis, United States
    Active

Researchers

  • Principal investigator: Iwelunmor, Juliet — Washington University
  • Study coordinator: Iwelunmor, Juliet

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.