Helping young children with Down Syndrome improve their thinking skills

Executive Function Intervention for Young Children with Down Syndrome

NIH-funded research Colorado State University · NIH-11135572

This project is developing a play-based program called EXPO to help young children with Down Syndrome strengthen important thinking skills, with caregivers leading the activities.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionColorado State University NIH-funded
Lab location1 site (Fort Collins, United States)
Project IDNIH-11135572 on NIH RePORTER

What this research studies

Young children with Down Syndrome often face challenges with executive functions, which are skills like planning, focusing, and problem-solving. This project is refining a 12-week program called EXPO, or "EXecutive Function Play Opportunities," that caregivers can use at home. EXPO is designed to build these thinking skills in a way that fits the unique strengths and challenges of children with Down Syndrome. We are gathering feedback from caregivers to make the program even better and more personalized, so it can help more children reach their full potential.

Who could benefit from this research

Good fit: Ideal candidates are young children with Down Syndrome and their caregivers who are interested in participating in a home-based, play-focused program.

Not a fit: Children who are older than the target age range or who do not have Down Syndrome may not receive direct benefit from this specific program.

Why it matters

Potential benefit: If successful, this program could provide young children with Down Syndrome a way to improve crucial thinking skills early in life, potentially leading to better adaptation and development.

How similar studies have performed: Preliminary testing of EXPO has shown promising results regarding its feasibility, acceptability, and initial effectiveness, indicating a strong foundation for this refined approach.

Where this research is happening

Fort Collins, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.